Pathophysiology of “cholinoceptor supersensitivity” in affective disorders
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چکیده
منابع مشابه
Pathophysiology of "cholinoceptor supersensitivity" in affective disorders.
Phenomenological and physiological variables demonstrate supersensitive changes to cholinergic challenge in affective disorder subjects. Theorists generally assume the primary defect is the postsynaptic muscarinic receptor. However, in addition to defectiveness or up-regulation of this receptor, the appearance of postsynaptic "cholinoceptor supersensitivity" can result from abnormal presynaptic...
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Introduction thal et al., 1984). This syndrome reportedly Seasonal affective disorder (SAD) is a synresponds to daily treatment with 2-6 hr of drome marked by recurrent depressions that bright artificial light (Lewy et al. 1982; Rogenerally occur in the fall or winter (Rosensenthal et al. 1984, 1986; James et al. 1985; Wehr et al. 1986). Neurobiological mechanisms accounting for the efficacy of...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 1986
ISSN: 0006-3223
DOI: 10.1016/0006-3223(86)90246-5